MONDAY, July 30 (HealthDay News) -- A new gene associated with a rare form of blindness from birth has been identified by researchers.
According to the report published online July 29 in the journal Nature Genetics, mutations in the NMNAT1 gene are linked to Leber congenital amaurosis (LCA), an inherited retinal degenerative disease that causes reduced vision in infants. Signs of vision loss are apparent in the first few months of life.
LCA is a common reason for enrolling children in schools for the blind.
This finding is a step forward in developing sight-saving gene therapy for patients with LCA, according to the researchers at the Massachusetts Eye and Ear Infirmary, the Children's Hospital of Philadelphia, Loyola University Chicago Health Sciences Division, and their colleagues.
"The immediate benefit of this discovery is that affected patients with mutations in this new LCA gene now know the cause of their condition," study co-senior author Dr. Eric Pierce, director of the Ocular Genomics Institute at Massachusetts Eye and Ear, said in an infirmary news release.
"Scientists now have another piece to the puzzle as to why some children are born with LCA and decreased vision. The long-term goal of our research is to develop therapies to limit or prevent vision loss from these disorders," Pierce said.
NMNAT1 is the 18th identified LCA gene and is located in a region known to harbor another LCA gene.
Leber congenital amaurosis occurs in about three of 100,000 newborns, and is one of the most common causes of blindness in children, according to the U.S. National Library of Medicine.
More information
The U.S. National Institutes of Health has more about Leber congenital amaurosis.
In this July 25, 2012 photo, Rob Manning, chief engineer, speaks to media at NASA Mars Yard at NASA's Jet Propulsion Laboratory in Pasadena Wednesday, July 25, 2012. Beside Manning is a model of the Mars rover, Curiosity. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/Nick Ut)
In this July 25, 2012 photo, Rob Manning, chief engineer, speaks to media at NASA Mars Yard at NASA's Jet Propulsion Laboratory in Pasadena Wednesday, July 25, 2012. Beside Manning is a model of the Mars rover, Curiosity. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/Nick Ut)
FILE - In this 2011 artist's rendering provided by NASA/JPL-Caltech, the Mars Science Laboratory Curiosity rover examines a rock on Mars. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/NASA/JPL-Caltech, file)
FILE - In this 2011 file artist's rendering provided by NASA/JPL-Caltech, a "sky crane" lowers the Mars Science Laboratory Curiosity rover onto the surface of Mars. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/NASA/JPL-Caltech, file)
This artists rendering provided by NASA shows the Mars Rover, Curiosity. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/NASA)
FILE - This Sept. 16, 2010 file photo shows engineers working on the Mars rover Curiosity at NASA's Jet Propulsion Laboratory in Pasadena, Calif. After traveling 8 1/2 months and 352 million miles, Curiosity will attempt a landing on Mars the night of Aug. 5, 2012. (AP Photo/Jae C. Hong, file)
PASADENA, Calif. (AP) ? NASA's new robot rover named Curiosity has spent 8? months hurtling through space toward its destination Sunday on Mars. It is set to land near the foot of a mountain rising from a giant crater. This marks NASA's 19th mission and eighth landing attempt.
Why Mars again?
The big unknown remains. Scientists want to know if any form of life ever existed there, and that means microscopic organisms. Since the 1960s, spacecraft have zipped past, orbited or landed on Mars in this quest. Two small NASA rovers that arrived in 2004 explored different craters and one is still functioning today.
Curiosity is the most ambitious effort ever, but it's not the be-all and end-all. During its two-year exploration, it will try to answer whether the giant crater where it lands had the right conditions to support microbes. But future missions would still be needed for more answers.
What will Curiosity do?
Curiosity carries a toolbox of 10 instruments, including a rock-zapping laser and a mobile organic chemistry lab. It also has a long robotic arm that can jackhammer into rocks and soil. It will hunt for basic ingredients of life including carbon-based compounds, nitrogen, phosphorus, sulfur and oxygen, as well as minerals that might provide clues about possible energy sources.
How did Curiosity get its name?
The spacecraft is formally called the Mars Science Laboratory. In 2008, NASA held a naming contest open to students and selected Curiosity, proposed by a sixth-grader from Lenexa, Kan.
What does this mission cost?
$2.5 billion. That's $1 billion over its original budget. Curiosity was supposed to launch in 2009 and land in 2010, but development took longer than expected. The delay gave engineers more time to debug problems and test the spacecraft, but also put the project over budget.
When will we send astronauts to Mars?
President Barack Obama has set a goal for astronauts to orbit Mars by the mid-2030s followed by a landing. Before that can happen, the plan is to send astronauts to an asteroid first.
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Follow Alicia Chang's Mars coverage at: http://www.twitter.com/SciWriAlicia
Health and Fitness | Dental Care | * Written by Peter Roseberg | Monday, 30 July 2012 04:05 | Word Count: 568
When people first hear about laser teeth whitening, they immediately envision long and painful hours spent at a dentist chair. Laser after all, is one word that is always synonymous with anything that destroys and deconstructs. While there are many whitening products that flood the market today, like whitening toothpastes, strips, rinses and tray-based tooth whiteners, mostly available over the counter or at the dentists? office, these products take their sweet time in whitening teeth. And more often than not, these products also whiten your teeth about one to two shades lighter, with results showing anywhere between 10-14 days. Some of them, like the rinses and strips need to be applied or done twice a day to get any visible results.?
The thing about laser teeth whitening or light-activated teeth whitening is that it is anything but painful or long. While it is agreeably one of the most expensive procedures one can go through for the sake of having whiter teeth, many previous patients swear by its effectivity which of course, is helped along with proper care and maintenance. A procedure done at the dentist?s office, it is one that is widely-used worldwide.?
It is a convenient all-in-one kit that already includes a tooth whitener, a bleaching light and mouth guards where the whitening gel is put in before it is placed over your teeth and activated by the bleaching light. The mouth guard also protects your gums from the whitening gel. The whole process begins when a dentist applies the whitening gel directly to the teeth and then using the bleaching light, which is made of mercury metal halide, activates and speeds up the whitening process. The Zoom Tooth Whitening South Melbourne process only takes between 30 minutes to an hour to do, but remarkable results can already be seen. Strategically placed and used correctly, the bleaching light is able to whiten the teeth from top to bottom simultaneously.? However, despite the rave reviews Zoom whitening gets from those who?ve already tried it and loved how it whitened their teeth, there are still some people who are hesitant about trying it out and so they should be. While it may be the most popular whitening treatment at the moment, it is still best to consult with a dentist to see if it is the best treatment for you. As a general rule, whitening procedures are recommended for people with healthy gums and unrestored teeth, and those with yellowish surface tones.?
The degree of whitening also depends on the original condition of the teeth and as mentioned, will last longer with proper care and maintenance ? and this includes avoiding any teeth-staining food or beverages. The good news is you may be able to have your teeth touched up a year or so after your initial treatment. With Zoom teeth whitening, however, you must do this once every 8 to 12 months and simply use over the counter whiteners in between to maintain the whiteness of your teeth. Too much Zoom whitening treatments may result in tooth dehydration because of the high levels of heat from the laser.?
Read up more on Zoom teeth whitening so you can decide if it really is the best way to bring out your best smile. Visit Whitenmysmile.com.au to find out more about Zoom Tooth Whitening Melbourne CBD.
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It is important that one trusts not only their dentist but also the treatments their dentists use to help them with their quest for whiter teeth. To better understand your whitening options, learn more about here.
Arnold Schwarzenegger turns 65 today. The Austrian-born bodybuilder, actor and former California governor has packed a lot of living into those six and a half decades.
The revelation in 2011 that he had fathered a child with a housekeeper and was separating from his wife, Maria Shriver, may have changed some fans' opinions of the actor, but he's still an A-list name. And once he left the governor's office, he was free to return to movies, where he is responsible for some?pretty memorable lines.
Here are a few of our favorites to honor the big guy's birthday.
1. "I'll be back." --"The Terminator
2.? "It's not a tumor!"? --"Kindergarten Cop"
3. "Hasta la vista, baby."? --"Terminator 2."
4. "Get to the chopper!"? --"Predator"
5. "To crush your enemies, see them driven before you, and to hear the lamentation of their women."? --"Conan the Barbarian"
6. "You should not drink and bake."? --"Raw Deal"
7. "Consider that a divorce."? --"Total Recall"
8. "If it bleeds, we can kill it."? --"Predator"
9. "The Iceman cometh!"? --"Batman?and Robin"
10. "Come with me if you want to live."? --"The Terminator"
Customers who are in search of for legal companies of personal injury lawyers normally count on word-of-mouth to get the very best professionals in managing their cases. Nevertheless, currently, a person would prefer to look for on the internet since he/she is aware of that there are trustworthy lawyers that they can employ in a number of web sites.
Perhaps as soon as in their lives, individuals would come across authorized difficulties on accidents, but they are not aware on the legal process. For that reason, in purchase to arm them with enough expertise in pursuing their circumstances in courtroom by way of the help of great legal professionals, right here are some tips that they ought to consider:
Tips in acquiring the very best private damage attorneys
Choosing an lawyer to go after an injuries circumstance in court docket is not as simple as several people think. One particular of the reasons is that a customer may possibly not be aware of litigation matters that could keep him/her asking yourself what is really going on, or for what are the expenses intended for.
A consumer might be thinking that the circumstance may possibly end up in a short period of time of time, but only to locate out afterwards that it?s extending to a more time courtroom struggle. Below are some great concepts to assist folks with authorized cases get the finest companies from individual harm lawyers:
. Constant communication ? This is important when the case is continuing to preserve the client properly informed of the attorney?s legal methods every single time that there?s court docket hearing. He must always give ample info on the advancement of the situation, how long would it consider, and the approximate price that it will incur.
Maintain in brain that an legal professional who neglects to keep you informed about the proceedings can surprise you of poor information in the conclude, and probably outcome in waste of time and money.
. Authorized costs ? When a customer hires his/her attorney, all fees that are incurred should be properly accounted for so that they could be included in the expenses if the circumstance wins.
. Experience and experience of the personalized harm attorneys ? Make a background check pertaining to his/her knowledge and experience in the exercise of legislation. Try out to find out how a lot of instances of the same character that he/she has already taken and won. Check also on the variety of several years that the attorney has specialised in pursuing situations associated to private damage regulation.
. Style of function ? This factor is important in analyzing the efficiency of the attorney. The customer ought to know if the lawyer is functioning by yourself or with an associate. If so, it should be known if the scenario is getting handed on to the companion who may possibly be much less seasoned in this kind of authorized circumstance. Try to observe also about his/her aggressiveness in court docket which could be detrimental at occasions.
. Expert community ? Check out if the law firm has a credible network of private injury lawyers and other professional specialists. Personalized harm circumstances may call for the testimony of an professional witness like a doctor. For that reason, when he/she calls a medical doctor to testify in court, he/she can very easily get the appropriate medical practitioner who is expert in that distinct harm.
. Store about for the finest lawyer ? Selecting an authorized practitioner ought to never ever be beneath hurry conditions. Normally, the inclination is to retain the services of someone who is not appropriate for the occupation, or a beginner in the occupation who cannot do a lot to get the scenario.
. Use of strong technologies ? This element permits personalized injuries attorneys to do their employment successfully, completely and efficiently.
In successful an damage circumstance, these important tips can help the clients properly in hunting for the appropriate lawyer, so, they must not be neglected.
Learn more about workplace injury raleigh. Stop by our site where you can find out all about workplace injury raleigh and what it can do for you.
Communication is the major backbone and ingredient in building intimacy in friendship. Its role cannot be overemphasized. This piece will put you in the know on how to build intimacy in friendship via communication. Intimacy results from a detailed knowledge of someone through close association as ideals, feelings, emotions, dreams, goals, likes, dislikes, attitudes and aspirations are shared. It is the experience of understanding and being understood by someone who loves and cares about you. This consequently leads to functional personal relationship.
Women get into intimate unions faster than men. For them deep communication results to intimacy and talking is a natural expression of womanhood but for men intimacy in communication is sometimes considered a threat to their masculinity. Between the sexes, communication means different thing. In women, mere talking could validate a relationship or what is being discussed. While in men, details of discussions are not necessarily important but its conclusion. Men never fix things which seem hazy to them unlike women who feel that a relationship that is worth anything is worth discussing. For women, the more they talk, the more intimate they believe relationship becomes. Men communicate from the level of the physical and facts, women from the level of emotions and feelings. Most men reach the limit of their ability to communicate when they express fact, but women go on to express their emotions. Everyone has a need to communicate; you should look for the level of communication that allows the most adequate expression of your message, ideas and feelings and present them in such a way that will be understood by the other party.
To communicate effectively, you have to meet each other on the same level, communication skills could be learnt no matter how you grew up or efficient you may be as a communicator. This skill could be acquired, provided you value a friendship or a relationship enough to work at it. Intimacy is not achieved overnight. It develops over a period of time as two relate to each other in an atmosphere of caring and warmth. It is not the end product of the time and effort given by friends who wants to remain in love with each other for a life time. When friends attain true intimacy through effective communication, their relationship will become the most meaningful and interesting one on earth. Intimacy further results when values, lifestyles, goals, and beliefs are shared through communication. Creating and achieving intimacy in your relationship is achievable through communication. It is important to know that intimacy is not built automatically, but it is generated through heartfelt communication over time. When the channel of communication is clear, it leads to understanding, and if unclear, it leads to confusion. As a vital link, it is capable of fastening deep relationships between people, if pursued, developed and maintained.
Communication is therefore the fuel that moves many friendships to an intimate relationship. For this communication to be effective, the message must be clearly passed or stated, concentration must be ensured, both parties must understand each other, and actions must be taken. Taking action which is the final route to intimacy (?INTO YOU (YOUR PARTNER) I SEE?) is like a reaction to the transactions between both parties to understand and appreciate each other. Intimacy on its own is the bedrock to spending a life time with your love one, it?s just like a stage when your heart beat corresponds with that of you partner, you see through his or her inner personality.
About the Author
EZE VICTOR OBINNA is a didactic motivational and inspirational speaker, counsels, speaks and writes on success, leadership empowerment, human potential and resource development, a public speaker with a mandate to empower millions around the world- in schools, churches, seminars, conferences, television and radio programmes. He joins the likes of Zig Ziglar, Myles muroe, Robert T. Kiyosaki, John C. Maxwell and others to educate, motivate and communicate the ideas and thoughts of great achievers of our race to the global world. He is a growing veteran entrepreneur with interest in real estate management, founder and editor-in-chief of the Great kings magazine, an author, a peer educator on HIV/AIDS and CEO of Great Kings Foundation. To contact or book him, Call 07033064775, 0818240335, e-mail ? Greatkingsfoundation@yahoo.com, join him on facebook at http://www.facebook.com/Ezevictorobinna
Streaming company Watchitoo (which powered the Social TV Summit stream) has launched a device to make it easier for producers to bring multiple live web streams straight to TV. ?The Watchitoo Channel Encoder 1000 is a server/hardware combination that can turn a web video stream into an HDTV-quality product by treating it like an in-studio camera feed,? the company explains.
TV producers are increasingly relying on live streams ? usually via Skype ? to book guests from around the world with minimal set-up. In the old days, booking a ?talkback? (as it?s often called) requires sending a microwave or live truck to the location, but as the quality of live video increased, web video chats are increasingly common on the air, from newscasts to syndicated talk shows. The Al Jazeera show, The Stream, is a great example of a show that relies on web streams to lower the barrier to booking guests all around the world.
As live web streams become increasingly common, Watchitoo?s new device is designed to help producers coordinate up to 25 at once, just like they?re studio camera shots. And you can imagine the possibilities for social TV: viewers could tap a button on their second screens to ask to be streamed live on the air. We spoke to Aviad Arviv, Watchitoo?s Chief Operating Officer, about the new device.
Lost Remote: How does the new tech work?
Aviad Arviv: Basically, it allows producers to stream multiple composite videos from the Watchitoo Live Show and broadcast directly into the studio with green room controls. These controls allow producers to prep guests and adjust audio and video feeds. Virtual guests can beam in from anywhere in the world. All the guest needs is a web cam and an internet connection.
The physical output from the WCE is HD/SDI. With the Admin the WCE comes with output resolution can be adjusted to support 1280?720 with a frame rate of 59.94 as needed in most TV studios.
LR: Why do TV broadcasters need this?
Arviv: This is a cost effective and innovative solution for bringing remote guests in virtually. The traditional model of having guests travel to the studio or sending production crews to broadcast via satellite is expensive and inefficient. There are other solutions that broadcasters have used and tested, but they do not have the capability of bringing multiple guests in remotely with the ability to control the source feed and pre-screen guests. This solution also allows broadcasters to move away from the linear approach of having multiple solutions to broadcast via TV & Web. The Watchitoo WCE is an integrated solution that allows broadcasters to bridge the gap between TV & second screen. We allow them to bring audiences from their web environment.
LR: How much will it cost?
Arviv: There are 2 models available ? a solution that can be installed in the studio or a SaaS-based solution. The cost varies and is customized based on the set-up and scale of the production, but typically covers set-up & installation and a subscription fee.
LR:?How will it make TV more social?
Arviv: More and more, TV is moving to the web, and we see this as an effective solution for broadcasters to provide second screen or original Web content programming. The Watchitoo platform enables web viewers to become part of the conversation with video chat, text, Twitter & Facebook posts; allowing anyone to be the star of the show.
Filed Under ?aviad arviv, channel encoder 1000, msos, MTV, o music awards, omas, Skype, social TV, the weather channel, Watchitoo, wce-1000, weather channel
Spanish unemployment is now near one quarter of the workforce, fuelling fears the country might need a costly bailout as the IMF issued its latest report on the eurozone's fourth biggest economy.
The unemployment rate rose in the second quarter to 24.63 percent of the workforce and to a huge 53 percent among the young, despite the start of the tourist season, figures from the national statistic office showed on Friday.
The increase in the overall jobless numbers was smaller than in the first quarter however, with the number of eligible people out of work rising to nearly 5.7 million people.
Between April and June, 53,500 people lost their jobs in Spain, compared with 365,900 in the first quarter, the national statistics office said.
The unemployment rate rose from 24.4 percent in the first quarter -- already the highest in the industrial world -- as Spain entered its third straight quarter of economic contraction.
And the International Monetary Fund warned Friday that the Spanish recession would be worse than initially expected, with a forecast contraction of 1.7 percent this year and of 1.2 percent in 2013.
Official Spanish economic growth figures for the second quarter are expected on Monday.
Spain's economy is reeling in the aftermath of a decade long real estate boom that crashed with the debt crisis, bringing the Spanish financial sector to the brink of insolvency.
Under pressure from European authorities who have agreed to bail out Spanish banks, Spain's conservative government has approved tens of billions of euros' worth of spending cuts, tax hikes and other measures.
Madrid must still pay high interest rates to borrow money on public debt markets, though the rate, or yield on benchmark 10-year bonds fell on Thursday and Friday following comments by European Central Bank chief Mario Draghi.
He declared on Thursday that the ECB was "ready to do whatever it takes to preserve the euro.
"And believe me it will be enough," Draghi added in comments that pushed yields on Italian and Spanish bonds lower because investors now expect the bank to buy debt issued by those countries, possibly in cooperation with their eurozone partners.
The stock exchange in Madrid has also leapt higher in the past two days, gaining 6.0 percent on Thursday and another 3.91 percent on Friday.
But the IMF, which wrote its report before Draghi's remarks had been made, said that heightened market tension could disrupt Spain's ability to finance itself despite a eurozone bailout worth up to 100 billion euros ($123 billion) agreed for Spanish banks and emergency financial reforms for the 17-nation bloc.
"Market tensions could intensify further, threatening market access, particularly if policies fail to stem capital outflows or due to further stress elsewhere in the euro area," the IMF said in a report.
Spanish Prime Minister Mariano Rajoy has scrambled to regain market confidence and unveiled his latest set of measures on July 11 aimed at saving 65 billion euros over three years.
Rajoy says the steps will help cut the public deficit in line with targets agreed with the European Union, and strengthen the economy in the long term.
Critics say the measures will make the poor suffer unfairly from moves such as a public sector bonus cut and a rise in sales tax that together will hit consumption.
"All the spending cut policies they are taking are restrictive and run counter to growth," said Alberto Roldan, an analyst at Spanish brokerage Inverseguros.
"Raising the fiscal pressure in a country with 25 percent unemployment is absolutely regressive."
Hundreds of thousands of Spaniards have marched across the country in recent weeks to protest against the measures.
The Spanish region hardest hit by rising unemployment was Catalonia in the northeast with a rate of 33.92 percent, Friday's figures showed. The lowest rate was 14.56 percent in the affluent Basque Country.
Concern that Spain might need a full bailout has grown since Spanish regions including Catalonia, the second biggest, said they too might need help from the federal government.
On Friday however, the government dismissed the prospect of an international rescue.
"A bailout is not an option," government spokeswoman Soraya Saenz de Santamaria said.
Pet dogs usually are not little humans and must not be treated as such. They think differently than individuals and should not be talked to as rational equals. If you believe your pet is thinking as a human, you will be dissatisfied. Keep to the suggestions because of this report, and you?ll be on the right track to having a well socialized puppy and how to Stop German Shepherd Scratching.
When you?re sensation frustrated or even impatient, quiet your self before beginning training. If you do not employ tolerance when training dogs, due to the fact . anxiety can cause pet dogs to get rid of emphasis.
If you self-discipline your pet, your own strengthen is a vital aspect. Pet dogs are in beat with individual inner thoughts and decide on high of that upward from your speech. A sufficient strict strengthen can help reinforce his or her discipline.
You?ll want to educate your pet to steer the right way making use of his tether. Suppose the lead as being a safety prerequisite.
To have good results within proper dog training, you need to be capable to control it using instructions. Your canine must help you like a chief, or they?re not going to comply with your own orders. By way of example, once you stroll your puppy you must take entrance and you will firmly insist your canine employs guiding a person.
You?re the chief and you will not really allow puppy decide when he would like to pay attention. If you fail to await your current order to get obeyed, don?t request everything of the family pet.
Avoid being embarrassed to ask for help if your training course doesn?t make positive changes to pet?s actions. Every pet is unique, if you will find that you will be having trouble training your dog, then a expert ought to come in and work with you. An experienced might help teach you the best methods to train, that may benefit your puppy.
Make certain your puppy increased and energetic usually. Canines are often uninterested. Also the bored to death canine is going to be much more obstinate through training. Once your puppy gets physical exercise, he?ll be a lot more comfortable and can pay attention with less effort. A good stroll or perhaps a fairly fast operate are fantastic methods for getting gone a few of your canine?s excess electricity.
Following understanding a few suggestions on the way to make it through for your canine and teach this to react to your anticipations you only need to adhere to your learning. Right after changing your pet dogs habits to suit with all the suggestions proposed you are able to correctly train your pet.
Marsha Branson has been a dog owner since childhood and a dog trainer and breeder for over 20 years. She is the owner of website German Shepherd Training . Visit the site for more information and for German Shepherd Training Tips
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Pull into port, get off that ship and go exploring!
When you?re deciding what to do for your next holiday, nothing says luxury more than taking yourself off on a cruise. Wherever you may go, you can guarantee that you?ll be pampered to the extreme, see an amazing range of sights, indulge in delicious food and experience something new every day. Sure, some days spent at sea mean that you?ll probably spend some time pottering about on board, but be sure to see what?s going on every time you pull into port. Life is nothing without a little exploration!
Limassol: loud and lively!
It?s easy to discover why Mediterranean cruises are growing in popularity. With so many different places to visit and wonderful weather throughout the year, such a trip is as close as you can get to guaranteed perfection no matter when you choose to travel. One definite high point of any cruise is a stop in Limassol, the vibrant city found on the gorgeous island of Cyprus that somehow manages to bring together a long history with a modern take on holidays.
Exploring the streets of the city will turn up all manner of wonders; exclusive shopping experiences and ancient buildings, bustling markets and charming tavernas packed out with locals that are always happy to welcome visitors to their tables. You?ll also see countless luxury hotels, so be sure to take notes in case you decide to come back to the island for a future visit. With so many hotels in Limassol, there?s something for every type of traveller.
Be sure to explore the best of Cypriot culture
Of course, you?ll be spending the night on your cruise liner, but if you feel like a day of pampering and relaxation in new surroundings, the many fine hotels are more than accessible to non-residents. Whether you want to find out exactly how good their spas are or just fancy grabbing a quick drink in one of their bars, you?ll be welcomed in at any time. It?s also a great way of discovering exactly what?s available to you during your limited time in the city, so don?t be afraid to ask the locals for some suggestions.
Venturing a little further out of the city will see the landscape turn from urban to something more natural, vineyards and olive gardens bursting with local produce that you?ll be dying to try. Heading back to the ship, you?ll be ready to answer everyone?s questions about what you saw on your travels. They might be surprised by the long list you?ve amassed!
Make certain to check us out if you?d like to discover a little more about hotels in Limassol and luxury hotels.
Lower vitamin D could increase risk of dying, especially for frail, older adultsPublic release date: 26-Jul-2012 [ | E-mail | Share ]
Contact: Ellen Smit Ellen.Smit@oregonstate.edu 541-737-3833 Oregon State University
CORVALLIS, Ore. A new study concludes that among older adults especially those who are frail low levels of vitamin D can mean a much greater risk of death.
The randomized, nationally representative study found that older adults with low vitamin D levels had a 30 percent greater risk of death than people who had higher levels.
Overall, people who were frail had more than double the risk of death than those who were not frail. Frail adults with low levels of vitamin D tripled their risk of death over people who were not frail and who had higher levels of vitamin D.
"What this really means is that it is important to assess vitamin D levels in older adults, and especially among people who are frail," said lead author Ellen Smit of Oregon State University.
Smit said past studies have separately associated frailty and low vitamin D with a greater mortality risk, but this is the first to look at the combined effect. This study, published online in the European Journal of Clinical Nutrition, examined more than 4,300 adults older than 60 using data from the Third National Health and Nutrition Examination Survey.
"Older adults need to be screened for vitamin D," said Smit, who is a nutritional epidemiologist at OSU's College of Public Health and Human Sciences. Her research is focused on diet, metabolism, and physical activity in relation to both chronic disease and HIV infection.
"As you age, there is an increased risk of melanoma, but older adults should try and get more activity in the sunshine," she said. "Our study suggests that there is an opportunity for intervention with those who are in the pre-frail group, but could live longer, more independent lives if they get proper nutrition and exercise."
Frailty is when a person experiences a decrease in physical functioning characterized by at least three of the following five criteria: muscle weakness, slow walking, exhaustion, low physical activity, and unintentional weight loss. People are considered "pre-frail" when they have one or two of the five criteria.
Because of the cross-sectional nature of the survey, researchers could not determine if low vitamin D contributed to frailty, or whether frail people became vitamin D deficient because of health problems. However, Smit said the longitudinal analysis on death showed it may not matter which came first.
"If you have both, it may not really matter which came first because you are worse off and at greater risk of dying than other older people who are frail and who don't have low vitamin D," she said. "This is an important finding because we already know there is a biological basis for this. Vitamin D impacts muscle function and bones, so it makes sense that it plays a big role in frailty."
The study divided people into four groups. The low group had levels less than 50 nanograms per milliliter; the highest group had vitamin D of 84 or higher. In general, those who had lower vitamin D levels were more likely to be frail.
About 70 percent of Americans, and up to a billion people worldwide, have insufficient levels of vitamin D. And during the winter months in northern climates, it can be difficult to get enough just from the sun. OSU's Linus Pauling Institute recommends adults take 2,000 IU of supplemental vitamin D daily. The current federal guidelines are 600 IU for most adults, and 800 for those older than 70.
"We want the older population to be able to live as independent for as long as possible, and those who are frail have a number of health problems as they age," Smit said. "A balanced diet including good sources of vitamin D like milk and fish, and being physically active outdoors, will go a long way in helping older adults to stay independent and healthy for longer."
###
Researchers from Portland State University, Drexel University of Philadelphia, University of Puerto Rico and McGill University in Montreal contributed to this study. It was funded in part by the National Institutes of Health and a grant from OSU.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Lower vitamin D could increase risk of dying, especially for frail, older adultsPublic release date: 26-Jul-2012 [ | E-mail | Share ]
Contact: Ellen Smit Ellen.Smit@oregonstate.edu 541-737-3833 Oregon State University
CORVALLIS, Ore. A new study concludes that among older adults especially those who are frail low levels of vitamin D can mean a much greater risk of death.
The randomized, nationally representative study found that older adults with low vitamin D levels had a 30 percent greater risk of death than people who had higher levels.
Overall, people who were frail had more than double the risk of death than those who were not frail. Frail adults with low levels of vitamin D tripled their risk of death over people who were not frail and who had higher levels of vitamin D.
"What this really means is that it is important to assess vitamin D levels in older adults, and especially among people who are frail," said lead author Ellen Smit of Oregon State University.
Smit said past studies have separately associated frailty and low vitamin D with a greater mortality risk, but this is the first to look at the combined effect. This study, published online in the European Journal of Clinical Nutrition, examined more than 4,300 adults older than 60 using data from the Third National Health and Nutrition Examination Survey.
"Older adults need to be screened for vitamin D," said Smit, who is a nutritional epidemiologist at OSU's College of Public Health and Human Sciences. Her research is focused on diet, metabolism, and physical activity in relation to both chronic disease and HIV infection.
"As you age, there is an increased risk of melanoma, but older adults should try and get more activity in the sunshine," she said. "Our study suggests that there is an opportunity for intervention with those who are in the pre-frail group, but could live longer, more independent lives if they get proper nutrition and exercise."
Frailty is when a person experiences a decrease in physical functioning characterized by at least three of the following five criteria: muscle weakness, slow walking, exhaustion, low physical activity, and unintentional weight loss. People are considered "pre-frail" when they have one or two of the five criteria.
Because of the cross-sectional nature of the survey, researchers could not determine if low vitamin D contributed to frailty, or whether frail people became vitamin D deficient because of health problems. However, Smit said the longitudinal analysis on death showed it may not matter which came first.
"If you have both, it may not really matter which came first because you are worse off and at greater risk of dying than other older people who are frail and who don't have low vitamin D," she said. "This is an important finding because we already know there is a biological basis for this. Vitamin D impacts muscle function and bones, so it makes sense that it plays a big role in frailty."
The study divided people into four groups. The low group had levels less than 50 nanograms per milliliter; the highest group had vitamin D of 84 or higher. In general, those who had lower vitamin D levels were more likely to be frail.
About 70 percent of Americans, and up to a billion people worldwide, have insufficient levels of vitamin D. And during the winter months in northern climates, it can be difficult to get enough just from the sun. OSU's Linus Pauling Institute recommends adults take 2,000 IU of supplemental vitamin D daily. The current federal guidelines are 600 IU for most adults, and 800 for those older than 70.
"We want the older population to be able to live as independent for as long as possible, and those who are frail have a number of health problems as they age," Smit said. "A balanced diet including good sources of vitamin D like milk and fish, and being physically active outdoors, will go a long way in helping older adults to stay independent and healthy for longer."
###
Researchers from Portland State University, Drexel University of Philadelphia, University of Puerto Rico and McGill University in Montreal contributed to this study. It was funded in part by the National Institutes of Health and a grant from OSU.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
The best thing that the parents think of when they decide upon buying their kids cell phones is that they can easily communicate with them as and when required and thus it will help them in worrying less about their child and also be able to contact them in needs of emergency. Most of the mobile manufacturing companies who manufacture specialized phones for kids are well aware of the dangers that the kids are exposed to if they misuse their cellular phone and hence adequate care is taken in order to bring enough parental control and also to restrict potentially harmful applications. Hence nowadays kids cell phones have become completely safe for each and every child.
As a small business owner or executive in a competitive field, it is an absolute should to preserve provider secrets just that, in order to survive. Employees divulge facts by way of text messaging and e-mail regularly, and dissatisfied workers can vent in many ways. There is also the value of honesty, exactly where GPS tracking can be applied to view the precise place of the employee?s phone. Quite a few workers abuse their phone privileges, and cell phone spying is a right that businesses have, in order to enforce their policies, and protect the company?s property.
You no longer have to succumb to old-fashioned spying where you have to literally tail behind your target like a desperate mad man or woman hoping to catch their prey on act, and losing your image and status for any mishaps that will result from the melodramatic scene. With the Cell Control spy software, you can finally uncover the TRUTH with style and grace!
You may uncover several advantages of using a program that enables one to spy on mobile cellphone texts. Children and teenagers use texts for some with their communications. With mobile phone spying, you can actually investigate those your toddlers offer with everyday. Since plenty of teenagers use various Internet web-sites to produce new pals, it is essential to have option of something excess to aid retain them secure.
You should know that there are companies out there who offer a spybubble service to the public. They?re known as ?reverse cell phone lookup websites? or ?reverse cell phone directories?. So if you type one of those two phrases into the Google search engine, you?ll return a bunch of companies who offer the service. Once you?ve found a service? you?ll probably need to register and pay the small fee right away, and that?s fine.
In the midst of the technological bliss that the whole world is experiencing as of today come the latest innovations and developments in looking up unknown owners of the numbers that have been calling you. Whether it is with regard to telephone numbers or mobile phone numbers, it does not matter. One particular field to keep focus on is the free cell phone number lookup service widely available in the internet and the commercial market as of today. It comes in two forms, first in software and second through any of the reverse mobile phone lookup service providing websites available in the web as of today.
Not only is this new cell phone text tracking good for family purposes but also great for any business. People concerned over a kids phone messages can certainly feel more at ease knowing all that is being sent. But businesses too can benefit knowing that employees are not taking advantage of being able to send a quick personal text message on company time.
This software has been manufactured for use on smartphones for example BlackBerry, iPhone and Android, and it is suitable for Windows Mobile, Symbian OS and iPad. After it is installed on a phone, the application boot styles up each and every time these devices is started up.
You can find a number of alternatives at your disposal when you really need a mobile phone trace. One example is, if you have the number, you can do a reverse directory search on it to learn who the owner is. These in most cases let you know a lot more information than merely the owner?s identity. You can usually also uncover where the account is located, the address associated with the account, any other phone numbers on the account, and which cellular phone supplier the account is on.
Are you currently suspecting your spouse or husband of unfaithful on you? With this event, a cell phone tracking method is the top matter you can use to test your hypothesis. You need to know that it is a piece of cake to use a monitoring application to find out if your wife or husband is really working late or just messing round.
A security code is a code that only the owner of the cell phone can decide. spybubble
A copy of the letter Boston's mayor sent to Chick-fil-A.
On the heels of Chick-fil-A president Dan Cathy's controversial public comments against same-sex marriage, Boston Mayor Thomas Menino fired off a letter to Cathy, urging him to abandon plans to expand the fast food chain to his city.
"In recent days you said Chick-fil-A opposes same-sex marriage and said the generation that supports it has 'an arrogant attitude,'" Menino wrote in a letter dated July 20 and published online Wednesday. "Now?incredibly?your company says you are backing out of the same-sex marriage debate. I urge you to back out of your plans to locate in Boston."
"I think we are inviting God's judgment on our nation when we shake our fist at him and say, 'We know better than you as to what constitutes a marriage,'" Cathy said in a recent radio interview. "I pray God's mercy on our generation that has such a prideful, arrogant attitude to think that we have the audacity to define what marriage is about."
In an interview with the Baptist Press published last week, Cathy doubled down on his stance against same-sex unions.
"Guilty as charged," Cathy said. "We are very much supportive of the family?the biblical definition of the family unit. We are a family-owned business, a family-led business, and we are married to our first wives. We give God thanks for that."
"We know that it might not be popular with everyone," he added, "but thank the Lord, we live in a country where we can share our values and operate on biblical principles."
All 1,608 of Chick-fil-A's restaurants are closed on Sundays, a day of rest for most Christians.
"Here in Boston, to borrow your own words, we are 'guilty as charged,'" Menino continued. "We are indeed full of pride for our support of same sex marriage and our work to expand freedom to all people."
Earlier this year, students at Northeastern University protested a proposal to put a Chick-fil-A on its Boston campus because of the company's history of supporting anti-gay organizations. The school abandoned its plan.
"The lower risk of endometrial cancer continued for older mothers across different age-at-diagnosis groups, including under 50, 50-59, 60-69, and over 70?which shows that the protection persists for many years," says study author Veronica "Wendy" Setiawan. (Credit: iStockphoto)
USC (US) ? Women who have their last baby in their 30s and 40s have a reduced risk of developing endometrial cancer, the most common gynecological cancer in the US.
New research finds that women who last give birth at age 40 or older have a 44 percent decreased risk of endometrial cancer, which strikes the tissue lining of the uterus, as compared to women who have their last baby younger than 25.
The study found that risk begins to decrease after age 30 by approximately 13 percentage points for each five-year delay in last births. Compared to women who last give birth before age 25, those who have their last child between age 30 and 34 reduce their risk by 17 percent and those between age 35 and 39 reduce their risk by 32 percent.
?While childbearing at an older age previously has been associated with a lower risk of endometrial cancer, the size of this study definitively shows that late age at last birth is a significant protective factor after taking into account other factors known to influence the disease?body weight, number of kids, and oral contraceptive use,?? says Veronia ?Wendy? Setiawan,? assistant professor of preventive medicine at the Keck School of Medicine at the University of Southern California.
Published online in the American Journal of Epidemiology, the study that is believed to be the largest of its kind, examined pooled data from four cohort studies and 13 case-control studies. Funded by the National Cancer Institute, the research examined a total of 8,671 cases of endometrial cancer and 16,562 control subjects, all derived from studies in the Epidemiology of Endometrial Cancer Consortium.
?We found that the lower risk of endometrial cancer continued for older mothers across different age-at-diagnosis groups, including under 50, 50-59, 60-69, and over 70?which shows that the protection persists for many years,? Setiawan says.
?Protection also did not vary by the two types of the disease: the more common Type 1, which we think is related to estrogen exposure; and the more rare, but more aggressive and deadly, Type 2, which has been thought to develop independent of hormones.?
Endometrial cancer is the fourth most common cancer diagnosed among American women. The American Cancer Society estimates that in 2012 about 47,130 new cases of cancer of the uterine body will be diagnosed, and about 8,010 women will die from such cancers. The vast majority of those cases are endometrial cancer.
Setiawan?s research also examines whether the association between age at last birth and endometrial cancer was consistent across race and ethnicity. The protective association was observed in Caucasian and Asian women, but not in the study?s small subset of black women, warranting additional study of larger groups of those women.
More research is necessary to determine why late age at last birth might protect against endometrial cancer, but Setiawan notes that several potential mechanisms have been suggested by other investigators, including:
Women capable of becoming pregnant at an older age may possess a healthy endometrium or experience fewer menstrual cycles without ovulation
Prolonged exposure to the hormone progesterone during pregnancy may be especially beneficial at older ages, the critical period for endometrial cancer development
Premalignant or malignant cells of the uterine cavity?s mucosal lining, which are more likely to exist with increasing age, are shed during childbirth.
?This study shows an important protective factor for endometrial cancer,? Setiawan says, ?and when the exact mechanism by which it protects women from getting the disease is known, it can help our understanding of how endometrial cancer develops and thus how to prevent it.?
The analysis was supported by the National Cancer Institute of the National Institutes of Health.
A totally harmonious relationship isn?t very common. Regrettably, disappointment and frustration is too widespread in relationships. Are you entirely happy in the relationship you?re in? If not, the wonderful news is that you can do various things to make certain you have a improved relationship. Use the following secrets and you?ll be on your way to a great relationship. Learn more down below to acquire ideas regarding free dating tips for men.
1. Commitment is Imperative
To savor a wonderful relationship, commitment is fundamental. When you?re in a relationship, your commitment ought to be be to making your relationship work. Understand that problems will occur from time to time. Your commitment and determination is needed from both partners, no matter how many problems there are.
2. Repair Instead of Restarting
Difficulties happen in every relationship. When you?re dealing with trouble, it?s uncomplicated to consider that being with another partner would be easier. Of course, instead of restarting your relationship with someone brand new, it?s the top proposal to work on repairing your current relationship.
3. Drop the Baggage
Stop living in a time warp and bid a last goodbye to any previous relationship. Otherwise, you are doing an injustice to your existing partner. Accomplish your personal potential and fulfill your goals while enhancing your relationship. Leave the past in the past and focus on the future of your relationship.
4.Don?t Let Children Get in the Way
Couples that have children sometimes let their children become a relationship problem. It?s simple for parents to turn their children into their single focus. If you let your children to get in the way of your relationship, when your children are gone, you?ll suddenly realize that you and your mate have grown apart and have nothing in common anymore. While your kids are definitely important you should make your relationship a high priority.
5. Relationships Shouldn?t Be Compared
It?s not a wonderful idea to compare your relationship with someone else?s. Each relationship is going to be different. Your happiness is not linked in any way with another couple?s happiness. Couples frequently make the error of trying to compare themselves to other couples who they feel are having a more pleasant relationship. Improve your own relationship but don?t try to measure it against someone else?s relationship.
6. Realize that Relationships Strengthenand Grow
Over time, relationships strengthen and grow. Your relationship is sealed together by a joint history of failure and success in your relationship. Keep in mind that change will occur in your relationship but it doesn?t have to be something negative. As you and your partner mature, your relationship will develop and start turning into a deeper and more special relationship.
7. Conviction is Essential
Conviction that your relationship is going to work will go a long way in ensuring that it does. Your happiness is something that will depend on you. You can have a fulfulling relationship as you have the conviction to back it up.
8. It Depends on Your Mindset
The happiness and success of a relationship depends a wonderful deal on your mind. Studies exhibit that hapiness is about your mindset and success, accomplishments and things don?t influence it. So make up your mind to be happy before you reach the end of life?s journey. This will benefit you and your relationship. To read much more dating associated details, just click here Tips To Have A Good Relationship.
The book has a different style to it.? While the story line moves forward in a straight manner, alternating chapters are written either by Brandy or her mother.? There are many asides and snarky comments spread throughout the book and they can distract from the story.? What I really liked about the book was the tip at the end of every chapter relating to antiques sales.? In this book Brandy and her mother have purchased a storage unit, so the tips relate to that type of antiquing.
After purchasing the unit Brandy and her mother move some of the items back to their house, including a cornet??allegedly belonging to Bix Beiderbecke. When they return for a second load, they find the locker empty except for the dead body of the owner of the storage facility.? The police arrive and they are not happy to see Brandy and her mother.? The book makes numerous references to other titles in the series, but I had no trouble following the story without reading any of the earlier books.? The story line winds it's way through the investigation, an attack on Peggy Sue and Sushi and more murders all related to the cornet.
This type of book is known as a "cozy mystery" and this one fits the bill.? An easy read it was none the less entertaining.
The classic View-Master toy gave a lot of us our first look at 3D images—a technology we would one day learn to despise. But that doesn't mean there still isn't a soft spot for those plastic goggles and paper discs in our hearts, which you can immortalize on your wall with this fantastic photo frame. More »
Streaming company Watchitoo (which powered the Social TV Summit stream) has launched a device to make it easier for producers to bring multiple live web streams straight to TV. ?The Watchitoo Channel Encoder 1000 is a server/hardware combination that can turn a web video stream into an HDTV-quality product by treating it like an in-studio camera feed,? the company explains. 
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Public release date: 26-Jul-2012
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